nope, they get along fine, fact. lol. actually how long do pakistani loaches get, think mine are at their biggest, but not to sure. if anyone has a snail problem, then these are the fish for you
yoyos can be aggressive if they're kept alone. I had 2 together that were rather aggressive...not to each other but to other fish. they're definitely best kept in trios as are clowns. a trio of each should be fine together.