I know you've been doing a lot of work and tinkering about with this very subject. How far do you realistically think you're away from running tanks that would never ever need water changes?
Purigen in a moving bed combined with (literally) the whole tank volume in denitrifying media in a slow flow reactor ( separate to the main aerobic filter) got me to consistently zero nitrates in a 180 pleco tank... but that didn’t make up for the evaporation demineralisation. I still did (albeit small) WC’s weekly.
Eventually I just gave it up ... was easier to do the WC’s.