4x Praziquantel Dose - Made a HUGE difference?
- Thread starter Miles
- Start date
nope only did the 4x.. I did a 4x dose with Jungle Anti-Parasite as well, but I noticed the formula with the acriflavine wasn't the ray's favorite and I got some cloudy water in the big tank when I did it to them.
I think the preliminary inference that can be drawn from this and other research into praziquantel & fish worming is that different bath concentrations can be more effective depending upon stocking density and duration of the bath. Rapidly reducing the prazi concentration after 24 hours would probably diminish toxicity, but may not reduce it to zero. Prazi-Pro is recommended to be dosed at 2.5 mg/l. A dosage 4x that would thus be close to 10 mg/l. Online research into worming fish often states that dosages closer to 1.5 mg/l are effective. I would agree that a 4x dose is arbitrary and even if apparently well-tolerated is rolling the dice unneccessarily.
I doubt that 5 small rays in a 100g tank require a bath concentration of 10 mg/l. Such a concentration may force more into their tissue and speed up the elimination of tapeworms and other internal worms, but at what cost? Lower (recommended) dosages have been proven to be effective. Miles has noted the obvious stress ray E is under. Could it not be just as likely that high concentrations of praziquantel aggravate stressing conditions and inhibit healthy activity? And if used in tanks that are "dirty", there could be serious chance of catastrophic reactions (dissolved oxygen, nitrogenous waste production increase, etc.).
I find this post stimulating, but I would be cautious to embrace this rather less-than-scientifically-rigorous hypothesis, particularly when there are known effective values for prazi concentration. Miles' dosing may well have merit, but further research would be needed. Still an excellent post.
I doubt that 5 small rays in a 100g tank require a bath concentration of 10 mg/l. Such a concentration may force more into their tissue and speed up the elimination of tapeworms and other internal worms, but at what cost? Lower (recommended) dosages have been proven to be effective. Miles has noted the obvious stress ray E is under. Could it not be just as likely that high concentrations of praziquantel aggravate stressing conditions and inhibit healthy activity? And if used in tanks that are "dirty", there could be serious chance of catastrophic reactions (dissolved oxygen, nitrogenous waste production increase, etc.).
I find this post stimulating, but I would be cautious to embrace this rather less-than-scientifically-rigorous hypothesis, particularly when there are known effective values for prazi concentration. Miles' dosing may well have merit, but further research would be needed. Still an excellent post.
Hi, anyone know the normal dose for pure plaziquentel powder? i read from koi forum last time and i remember is 7g for 1000g. any info for the dose for ray will be much appreciated.
royalray;1810645; said:
4x the normal dose of PraziPro works..
Might read this stuff.. http://www.colszoo.org/internal/ela... Notes on Reproduction of the Zebra Shark.pdf
There is another article in the manual somewhere that gives more specifics for meds..
Also look at the Stingrays and Medications sticky at the top of the section.
So, Miles, how did ray E react to the 4x dose of Prazi in the 50g bath? Has his stress been reduced? Is there still white feces? I want an update! LOL!
