I'm pretty sure Paraguard works better as a topical for open wounds, but I haven't found it very effective for bacterial infections. Paraguard requires dosing every day and when using a water conditioner, you need to wait a few hours after a water change, and then redose with paraguard.
I personally would try the Sulfaplex first (as an antibiotic).
Oh thanks for that, i will prepare the water tonight for the change, and put a heater in the bucket to ensure good temperature, that will give it 10hours to stand after water conditioner and should be ready for use. all this information is going into my note book. We have saved his life once before. he jumped out the fish tank, and when i noticed, he didnt look to good on the floor. How he got out the cover is still a mistery. anyway we nursed him back to health, and now this. I have 6 other polyeterus, and none of them have given me as much trouble as this little man. This little man is only about 6mnth old, my others are 3/4 years old. (ornate, delhezi, sengal, albino senegal and 2 others that i can remember their names) oh not all in the same tank.
thank you very much for your advise, greatly appreciate