Unfortunately the best answer is maybe. You will hear success stories and horror stories, not just with Jag, JD combinations either. Given a big enough tank your chances of success increase considerably. JDs for the most part are not overly aggressive so if you have a tolerant Jag they could live together. The best advice would be plan for the worst and hope for the best, no one can say yes it will work or no it wouldnt work. It depends on the disposition of the individual fish in question. Good luck with them.