The 2260 uses the model 1260 pump which is 2400 lph but you usually have to purchase the double tap fittings (quick disconnects) separately so that will add to the price of the filter if you buy them.
One 2260 may be sufficient on a 125G tank depending on the fish stocking levels and fish size for filtration. Powerheads are normally used for water movement and not filtration, so you may or may not need any.
One 2260 may be sufficient on a 125G tank depending on the fish stocking levels and fish size for filtration. Powerheads are normally used for water movement and not filtration, so you may or may not need any.