Like I said, there is lots and lots that can be written about the effects of processing and cooking food. You can "replace" naturally occurring vitamins in food with manufactured ones to compensate for what was lost in processing. You can't rebuild certain amino acids and enzymes. Once cooked their potency is greatly reduced or lost entirely. Nothing to debate here. Some pellets can provide adequate nutrition (most don't), just not excellent nutrition. Koi breeders have known this for 100's of years and even when using the most expensive advanced diets in the world, and the natural advantages that koi have in digesting plant material, when it comes time to pick between pellets and a natural diet for a $250,000 fish, the best breeders use a natural diet for robust growth.
The quote below relates to raw milk. Milk is a rich source of protein and the effects of pasteurizing are well understood.
From: http://www.raw-milk-facts.com/raw_milk_health_benefits.html
Raw cow's milk has all 8 essential amino acids in varying amounts, depending on stage of lactation (8). About 80% of the proteins in milk are caseins- reasonably heat stable and, for most, easy to digest. The remaining 20% or so are classed as whey proteins, many of which have important physiological effects (bioactivity) (9). Also easy to digest, but very heat-sensitive (10), these include key enzymes (11) (specialized proteins) and enzyme inhibitors, immunoglobulins (antibodies) (12), metal-binding proteins, vitamin binding proteins and several growth factors.
The quote below relates to raw milk. Milk is a rich source of protein and the effects of pasteurizing are well understood.
From: http://www.raw-milk-facts.com/raw_milk_health_benefits.html
Raw cow's milk has all 8 essential amino acids in varying amounts, depending on stage of lactation (8). About 80% of the proteins in milk are caseins- reasonably heat stable and, for most, easy to digest. The remaining 20% or so are classed as whey proteins, many of which have important physiological effects (bioactivity) (9). Also easy to digest, but very heat-sensitive (10), these include key enzymes (11) (specialized proteins) and enzyme inhibitors, immunoglobulins (antibodies) (12), metal-binding proteins, vitamin binding proteins and several growth factors.