That is definitely a lot of big fish in a 180gal tank, so major bioload. Your biomedia is not enough to keep up with the waste being produced. With that much of a bio-load and that relatively small volume of water, you're going to need to do at least 50% w/c every other day (possibly everyday) just to keep up.
I think your options are lots and lots of daily w/c, get a much larger tank, or significantly reducing stock.
I think your options are lots and lots of daily w/c, get a much larger tank, or significantly reducing stock.