I was asked by Lupin to start this thread here. I recently started to have some fish die suddenly with strange syptoms of : flashing, turning dark and sulking ,then swimming in circles,sometimes spinning, smashing into tank sides, and death follows shortly. I have been using prime for my water changes .I was talking with a fellow hobbiest who had some fish die suddenly also, he recently used prime and lost some very hardy fish also . I have switched back to amquel and did water changes on 2 tanks and the fish are acting so much better. One of the tanks has 2 large peacock bass in it , and one fish was starting to get the syptoms I described,and when I did the water change with amquel his symptoms have gone . The other tank has 5 small Peacock bass in it ,and normally when I do a water change with prime they hang out under the water return for a day or so,and seem a little uncomfortable, and they won`t eat right away . When I did the water change with amquel they were happily feeding right away and swimming aroiund the tank normally. I have heard from a few people that thier fish act strange/uncomfortable if they use prime. Does anyone else having any problems or strange symptoms happening soon after water changes ?