I have to admit that I would NOT use the Mag350 as a primary filter. I would deff go for an AC110 or even a diffrent canister (XP3, FX5, Ehiem 238923485239) But I do love my mag 350, it really cant be beat for an off the shelf mech/chem filter, and if things get really messy you can always load the micron cartredge with DE and boom its a diatom filter. You can put carbon/peat/argonite ect buffers or even ceramic rings if you wanted into the basket and run that as well. Its a very versatile and handy secondary filter but I would deff get somthing els to handle your bio.