I like using styrofoam as a cushion for rocks, it disperses weight and cushions in case of shifting.
Have you chemically tested that rock, depending on its composition it could cause PH/GH/KH changes.
In order for water to have a positive effect on the weight of a object the object have to have some degree of bouyancy, Positive vs Negative bouyancy.
What it will have a effect on is the weight of the total tank/stand setup, this is due to water displacement.
Regardless,
a 50lb rock, negative bouyancy, exerts 50lbs of pressure on a single point of contact.