I mix my saltwater in a bucket with a powerhead for at least a day. Test the specific gravity frequently to make sure it is where I want it (1.023 or so). It does take time for all the salt crystals to completely dissolve, even when using Instant Ocean. Are you going to use RO water or tap water?
I think you should keep the specific gravity in your tank as close to natural seawater. Some people keep theirs lower. Use a qt tank for that. And I throw a heater in the bucket a few hours before doing a water change. Test the sg again as temperature can affect it.
What size tank do you have? I would add live rock now and test for ammonia, nitrite, and nitrate. Once your live rock has "cured" and the tank is cycle, you can add a fish.
You might want to upgrade your skimmer too. Skilters really don't do much as far as skimming goes.