I went play sand on my 75 gallon. For fish only its fine I guess. But it does contain a crap ton of silica, in which diatoms build on, in which brown algae will feed (crap is like fertilizer) if your nitrates start to run high....and trust me it's a nightmare when this happens lol
Also on a tank that large (220), play sand is going to take forever to settle, we are talking days here. And this is every time you vacuum, knock it up into the water etc. It's super thin and almost dust like in my experience. It will also fill your XP3 up with sand if you run the intake low. It did mine at least.
I am building a 135 gallon right now, and am only using live sand mixed with a few pounds of Aragonite. Figured I would do it right this time around lol