Personally, I'd worry about the Puffers mistaking the Kuhli for a worm (DINNER!!!), but is appears that a few people on here have had success with it. If you did decide to go with them, I'd make sure your filters are safe so they don't get stuck and that the Kuhlis have adequate hiding places. Also, sharp/rough rocks are not recommended due to their lack of scales. They can get abrasions and lacerations that will then have the chance of getting infected. Personally, I like otos: they are algae eating machines; they are crazy fast; and I have had no trouble with my puffer and oto before, granted I don't have Dward [evil] puffers ;D.