Lumps on fins, what are they?

[Aquanero]

3X is safe to use with Kanamycin or I would not have suggested it. I would not use it with Tetracyclines or Erithromycin. Both meds act differently and have different modes of operation. Kana prevents the bacteria from being able to synthesize proteins while Sulfa drugs prevent the synthesis of folic acid in cells. Truth be told I would have rather seen this treated first with the 3X over the Kanamycin and even used in conjuction with Malachite Green administered as a bath for this before bringing in the the Kanamycin and using it only if this was considered a systemic issue which it doesn't appear to be.

 

[Psylant]

I only had a few medications kicking around. Kanaplex seemed to be the only obvious choice. I think I also have some Metro, Focus, and some ich medications that all came with my 450g. Do you think I should buy some of the Triple Sulfa? Will it be more effective at treating a raw, scaleless patch that is flesh colored about 2" square? My PH is about 8.0. I have very hard calcified water. As of when I went to sleep last night he was seemingly relaxed in the tub. He only splashed once and was quiet the rest of the night. I checked on him a couple times but have left the lid on most of the time so it's dark and he can't escape. All I look for is to see if he's still moving at all.

I'm not sure he's going to pull through, but I'd be sad to see him go. He's my favorite fish of all time by a long shot.

 

[Aquaticfan]

3X is safe to use with Kanamycin or I would not have suggested it. I would not use it with Tetracyclines or Erithromycin. Both meds act differently and have different modes of operation. Kana prevents the bacteria from being able to synthesize proteins while Sulfa drugs prevent the synthesis of folic acid in cells. Truth be told I would have rather seen this treated first with the 3X over the Kanamycin and even used in conjuction with Malachite Green administered as a bath for this before bringing in the the Kanamycin and using it only if this was considered a systemic issue which it doesn't appear to be.

 

[Aquanero]

I would try to treat with the 3x. If the fish is fighting give it a chance. Another member had a TSN that was on deaths door and she brought it back with treatment, don't give up.

 

[Aquaticfan]

I would try to treat with the 3x. If the fish is fighting give a chance.

I'd agree 100% with Tom.

For bacteria infection such as columnaris and others the combination of kanamycin and triple sulfa (or furan 2 aka nitrofurizone )are well know for corresponding ph levels as Tom has pointed out vs the kanamycin and furan 2 combination. I'd also at this point also recommend to keep temps below or at 75 degrees. Temps in the 75 and under range have better o2 levels and have shown to hinder/slow bacteria advancement allowing treatment to become effective.

The reason for dosing both medications at the same time is identification of a specific bacterial or fungal pathogen is not often possible from mere visual inspection of the symptoms on the fish.By using broad-spectrum treatments such as these combinations you effectively cover more potential problems safely and effectively. In the case of columnaris flexobacterium the minimum inhibitory effectiveness of each medication is to low. As well as they work on different levels. One (kanamycin) actually will soak into the tissues and the other (triple sulfa and furan 2) does not. The one can act as a carrier to the other to make it more effective.

Kanamycin,*nitrofurizone*and metronidazole can all actually be safely used together for parasitic, fungal, & bacterial infections in the same treatment.


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[Aquanero]

^ Very good!

 

[Psylant]

Very helpful information. I appreciate it very much. Thank you. It makes sense to be careful when mixing these powerful chemicals, but it also makes a lot of sense to have a very broad coverage since diagnosis is difficult.

He's still alive, but it's difficult to tell much else in his dark tub. I turned the temp down to 75 as recommended. I have some Metro on hand, as well as Focus and Polyguard. Do you feel I should add anything else that I have on hand? I won't be able to grab the Triple Sulfa for a couple days at best. I don't make many trips into the city -- especially at this time of year.

 

[RD.]

Gents, I'm well aware of the fact that these meds are commonly mixed when treating things such as columnaris, but this isn't columnaris! In fact, none of the meds mentioned are completely "safe", and all of them can have negative long term effects on fish. Unless I'm missing something, this bacterial infection probably surfaced when the fry from this recent spawn began feeding on this males slime coat. It's a common thing with large CA's, and was a good catch by slayer. IMO Kanamycin IS a good broad spectrum antibiotic, that probably in this case was more than enough to deal with what has been described by the OP as " a raw, scaleless patch that is flesh colored about 2" square? ".

Personally I would have treated with clean water, and salt. But hey, that's just me.

 

[Psylant]

Gents, I'm well aware of the fact that these meds are commonly mixed when treating things such as columnaris, but this isn't columnaris! In fact, none of the meds mentioned are completely "safe", and all of them can have negative long term effects on fish. Unless I'm missing something, this bacterial infection probably surfaced when the fry from this recent spawn began feeding on this males slime coat. It's a common thing with large CA's, and was a good catch by slayer. IMO Kanamycin IS a good broad spectrum antibiotic, that probably in this case was more than enough to deal with what has been described by the OP as " a raw, scaleless patch that is flesh colored about 2" square? ".

Personally I would have treated with clean water, and salt. But hey, that's just me.

I trust your opinion, Neil. The fact that this is common and may only be from the fry nipping at him makes me feel a lot better. I hope it heals without much scarring, assuming he survives. I think I'll just keep up with the Kanaplex dosing to ensure there is nothing funky going on with the fleshy patch. In 2 weeks or so I will try re-introducing him back into the community and removing all of the fry to the tub. I wish I had another tank and didn't have to use a tub for all of this...

I'll post updates as they come. I love this forum. Thanks for the advice everyone!

 

[Aquanero]

I have to disagree. No one said this is columnaris. Columnaris is not the only thing these are used for, a secondary infection can be caused by many pathogens and 3x IS the med for this. I don't doubt the fry ate the slime coat but once the slime coat is compromised the bacteria could care less what caused it. Kanamycin is an excelent anitbiotic and is very useful in this type of water but it is not the best choice in this instance. I would save the Kana for somthing it was intended for and not just throw it at this. The Op seems to trust your judgement so I'll not comment further on any potential course of action regarding this issue.