I think the biggest, and the one that hurt the most, was buying ghost shrimp for my tank.
I had a 125 set up with my favorite fish, a long nosed elephant nose. He was awesome, never hid, and would eat out of my husband's hand. He was a beggar, and was just the most awesome fish. We "rescued" him from a LFS, he was in a 20 gallon with no hides, and 100 little neons. He was going nuts, and banging into the sides of the tank. We had to have him.
I noticed he was missing. I figured he was just hiding, but we decided to look for him. Nothing, and no dried up fish on the floor. But, when moving logs and rocks, we found this HUGE crayfish, that must have come in with a load of ghost shrimp that we had bought. Couldn't have been very big when he came in, but he obviously ate well.
A few days later, we had a clogged canister filter. We found a skeleton in the intake...must have been my elephant nose. I am guessing that the crayfish got him while he was asleep. That really hurt.